Search results for "noninvasive imaging"

showing 9 items of 9 documents

Hunting for the high-affinity state of G-protein-coupled receptors with agonist tracers: Theoretical and practical considerations for positron emissi…

2019

Abstract The concept of the high‐affinity state postulates that a certain subset of G‐protein‐coupled receptors is primarily responsible for receptor signaling in the living brain. Assessing the abundance of this subset is thus potentially highly relevant for studies concerning the responses of neurotransmission to pharmacological or physiological stimuli and the dysregulation of neurotransmission in neurological or psychiatric disorders. The high‐affinity state is preferentially recognized by agonists in vitro. For this reason, agonist tracers have been developed as tools for the noninvasive imaging of the high‐affinity state with positron emission tomography (PET). This review provides an…

Central Nervous SystemBETA-ADRENERGIC-RECEPTORpositron emission tomographyagonist high-affinity stateD-2/3 AGONISTG-protein-coupled receptorsReview ArticleReceptors G-Protein-Coupledchemistry.chemical_compound0302 clinical medicineDrug DiscoveryReceptorNeurotransmitterReview Articles0303 health sciencesmedicine.diagnostic_testNONHUMAN PRIMATE BRAINEndocytosisTEST-RETEST REPRODUCIBILITYPositron emission tomographyG‐protein‐coupled receptors030220 oncology & carcinogenesisENDOGENOUS OPIOID RELEASEMolecular MedicineIN-VIVO BINDINGSignal TransductionAgonistNoninvasive imagingexperimental designmedicine.drug_classNeurotransmissionRAT-BRAINneurotransmittersagonist high‐affinity state03 medical and health sciencesIn vivomedicineAnimalsHumanshuman brain030304 developmental biologyG protein-coupled receptorPharmacologyDOPAMINE D2(HIGH) RECEPTORS5-HT1A RECEPTORSchemistryPositron-Emission TomographyPET RADIOLIGANDRadiopharmaceuticalsNeuroscienceMedicinal research reviews
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Noninvasive Imaging Estimation of Myocardial Iron Repletion Following Administration of Intravenous Iron : The Myocardial- Trial

2020

Background Intravenous ferric carboxymaltose ( FCM ) improves symptoms, functional capacity, and quality of life in heart failure and iron deficiency. The mechanisms underlying these effects are not fully understood. The aim of this study was to examine changes in myocardial iron content after FCM administration in patients with heart failure and iron deficiency using cardiac magnetic resonance. Methods and Results Fifty‐three stable heart failure and iron deficiency patients were randomly assigned 1:1 to receive intravenous FCM or placebo in a multicenter, double‐blind study. T2* and T1 mapping cardiac magnetic resonance sequences, noninvasive surrogates of intramyocardial iron, were eval…

MaleCardiac magnetic resonance*ferric carboxymaltoseMagnetic Resonance Imaging (MRI)Myocardial ironAnèmia*heart failure030204 cardiovascular system & hematologyFerric Compounds0302 clinical medicine030212 general & internal medicineOriginal Researchcardiac magnetic resonance ferric carboxymaltose heart failure iron deficiency myocardial ironAnemia Iron-DeficiencyAnemiaIron deficiencyMiddle AgedMyocardial ironMagnetic Resonance Imaging*myocardial ironMagnetic resonanceCardiologyAdministration IntravenousFemaleCardiology and Cardiovascular Medicine*cardiac magnetic resonancemedicine.medical_specialtyNoninvasive imagingCardiomyopathyIronIntravenous ironHeart failureFERRIC CARBOXYMALTOSE03 medical and health sciencesDouble-Blind MethodInternal medicinemedicineHumansMaltoseAgedPharmacologybusiness.industryMyocardiumIron deficiencyRessonància magnèticaMiocardimedicine.diseaseFerric carboxymaltoseTreatmentHeart failureHematinicsbusinessCardiac magnetic resonance*iron deficiencyFerro
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Noninvasive Visualization of an Apparent Patent Intracoronary Stent by Transesophageal Echocardiography

1995

In the area of increasing interventional techniques there is a need for noninvasive imaging modalities to provide postinterventional follow-up. We were able to visualize the apparent patency and measure the dimensions of an intracoronary Palmaz-Schatz stent in the left circumflex coronary artery using transesophageal two-dimensional echocardiography. This report indicates the potential of echocardiography to directly assess coronary stents.

Malemedicine.medical_specialtyNoninvasive imagingIntracoronary stentmedicine.medical_treatmentCoronary DiseaseCoronary AngiographyInternal medicinemedicineHumansRadiology Nuclear Medicine and imagingcardiovascular diseasesAngioplasty Balloon CoronaryVascular PatencyInterventional cardiologybusiness.industryStentMiddle Agedequipment and suppliesCoronary VesselsCardiologyLEFT CIRCUMFLEX CORONARY ARTERYStentsRadiologyCardiology and Cardiovascular MedicinebusinessEchocardiography TransesophagealEchocardiography
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Real-time ultrasonography in the otolaryngology office setting

1993

Over the past two decades, diagnostic ultrasonography has evolved into an extensively used noninvasive imaging modality. It plays a vital role in the disciplines of vascular surgery, cardiology, neonatology, pediatrics, ophthalmology, gynecology, and urology, to name a few, but it is in the field of obstetrics that this technology has been maximally used as an office procedure to evaluate the status of the fetus. In the evaluation of head and neck disorders, ultrasonography has been the subject of sporadic reports for the past 15 years.le3 However, except for the evaluation of thyroid masses,4 it has never been widely accepted in the United States as a diagnostic modality, and has taken a b…

Malemedicine.medical_specialtyNoninvasive imagingTime FactorsModality (human–computer interaction)medicine.diagnostic_testbusiness.industryMEDLINEMagnetic resonance imagingVascular surgeryPhysicians' OfficesSurgeryOtolaryngologyOtorhinolaryngologyOtorhinolaryngologyNeoplasmsmedicineHumansFemaleMedical physicsReal time ultrasonographyHead and neckbusinessUltrasonographyAmerican Journal of Otolaryngology
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Determination of Bubble Size Distribution Using Ultrasound Array Imaging

2020

In this article, ultrasonic phased arrays are deployed as an imaging tool for industrial process analysis. Such arrays are typically used for sonar, medical diagnosis, and nondestructive testing; however, they have not yet been applied to industrial process analysis. The precise positioning of array elements and high frequencies possible with this technology mean that highly focused images can be generated, which cannot currently be achieved using ultrasound tomography. This article aims to highlight the potential of this technology for the measurement of bubble size distribution (BSD) and to demonstrate its application to both intrusive and noninvasive process measurements. Ultrasound imag…

Materials scienceAcoustics and UltrasonicsPhased arrayultrasound array imagingTKAcousticsBubbleImage processingtotal focusing method (TFM)01 natural sciencesSonar/dk/atira/pure/core/keywords/engineering_mathematics_research_groupnoninvasive imagingSettore ING-IND/14 - Progettazione Meccanica E Costruzione Di MacchineNondestructive testing0103 physical sciencesImage Processing Computer-AssistedElectrical and Electronic EngineeringBubble size distribution (BSD)010301 acousticsInstrumentationUltrasonographyEngineering Mathematics Research Groupbusiness.industrybubble size distributionEquipment DesignSizingtotal focusing methodUltrasound TomographyModels ChemicalUltrasonic sensorbusinessindustrial process analysisAlgorithms
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Application of Infrared Thermography in the Assessment of Sport Equipment

2019

Abstract Infrared thermography is a noninvasive imaging technique used to determine surface temperatures under controlled conditions. This technique has many applications in different fields, the assessment of sport equipment being one of them. This chapter aims to provide a general overview of the scientific literature regarding the application of infrared thermography for the assessment of sport equipment. Some examples are provided based on the recent literature and the background experience of the chapter authors in the use of infrared thermography in sport. Examples include the monitoring of formula one (F1) tires during racing, detection of technological doping in cycling, saddle fit …

Noninvasive imagingEngineeringbusiness.industryThermographyTennis racketMechanical engineeringbusiness
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Visualizing cell death in experimental focal cerebral ischemia: promises, problems, and perspectives

2011

One of the hallmarks of stroke pathophysiology is the widespread death of many different types of brain cells. As our understanding of the complex disease that is stroke has grown, it is now generally accepted that various different mechanisms can result in cell damage and eventual death. A plethora of techniques is available to identify various pathological features of cell death in stroke; each has its own drawbacks and pitfalls, and most are unable to distinguish between different types of cell death, which partially explains the widespread misuse of many terms. The purpose of this review is to summarize the standard histopathological and immunohistochemical techniques used to identify …

Noninvasive imagingProgrammed cell deathIschemiaComplex diseaseContext (language use)Review ArticleBrain IschemiaBrain ischemia03 medical and health sciences0302 clinical medicineNeuroimagingmedicineAnimalsHumansStroke030304 developmental biology0303 health sciencesMicroscopyCell Deathbusiness.industryBrainmedicine.diseaseImmunohistochemistryMagnetic Resonance ImagingStrokeNeurologyNeurology (clinical)Cardiology and Cardiovascular MedicinebusinessNeuroscience030217 neurology & neurosurgeryJournal of Cerebral Blood Flow & Metabolism
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Contrast-Enhanced Magnetic Resonance Angiography of the Pulmonary Vasculature

1998

Magnetic resonance angiography (MRA) has been established as a powerful noninvasive imaging modality. Its applications to the study of the pulmonary vasculature have been hampered by a multitude of factors, such as respiratory and cardiac motion artifacts, saturation problems, long acquisition times

Noninvasive imagingmedicine.medical_specialtygenetic structuresmedicine.diagnostic_testbusiness.industryGeneral Medicineequipment and suppliesMagnetic resonance angiographyCardiac motioncardiovascular systemmedicineRadiology Nuclear Medicine and imagingPulmonary vasculatureRadiologybusinesscirculatory and respiratory physiologyInvestigative Radiology
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Noninvasive cardiovascular imaging for evaluating subclinical target organ damage in hypertensive patients: a consensus article from the European Ass…

2017

International audience; : Arterial hypertension accounts for the largest amount of attributable cardiovascular mortality worldwide, and risk stratification in hypertensive patients is of crucial importance to manage treatment and prevent adverse events. Asymptomatic involvement of different organs in patients affected by hypertension represents an independent determinant of cardiovascular risk, and the identification of target organ damage is recommended to further reclassify patients' risk. Noninvasive cardiovascular imaging is progressively being used and continues to provide new technological opportunities to target organ damage evaluation at early stage. The aim of this article is to pr…

cardiovascular riskRiskarterial hypertensionmedicine.medical_specialtyNoninvasive imagingPhysiologyPopulation030204 cardiovascular system & hematologyAsymptomatic03 medical and health sciences0302 clinical medicinetarget organ damageInternal medicineInternal MedicineHumansMedicineIn patient030212 general & internal medicineAdverse effectIntensive care medicineeducationSocieties MedicalCardiovascular mortalitySubclinical infectionCardiac Imaging Techniqueeducation.field_of_studybusiness.industrynoninvasive cardiovascular imagingTarget organ damage3. Good healthCardiac Imaging TechniquesHypertensionPractice Guidelines as TopicCardiology[SDV.IB]Life Sciences [q-bio]/Bioengineeringmedicine.symptomCardiology and Cardiovascular MedicinebusinessprognosiHuman
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